Recent Pubs

N. Kerur; S. Fukuda; D. Banerjee; Y. Kim; D. Fu; I. Apicella; A. Varshney; R. Yasuma; B.J. Fowler; E. Baghdasaryan; K.M. Marion; X. Huang; T. Yasuma; Y. Hirano; V. Serbulea; M. Ambati; V.L. Ambati; Y. Kajiwara; K. Ambati; S. Hirahara; A. Bastos-Carvalho; Y. Ogura; H. Terasaki; T. Oshika; K.B. Kim; D.R. Hinton; N. Leitinger; J.C. Cambier; J.D. Buxbaum; M.C. Kenney; S.M. Jazwinski; H. Nagai; I. Hara; A.P. West; K.A. Fitzgerald; S.R. Sadda; B.D. Gelfand; J. Ambati. cGAS drives noncanonical-inflammasome activation in age-related macular degeneration. Nature medicine 2018 Jan
B.D. Gelfand; J. Ambati. A Revised Hemodynamic Theory of Age-Related Macular Degeneration. Trends in molecular medicine 2016 Aug
R. Yasuma; V. Cicatiello; T. Mizutani; L. Tudisco; Y. Kim; V. Tarallo; S. Bogdanovich; Y. Hirano; N. Kerur; S. Li; T. Yasuma; B.J. Fowler; C.B. Wright; I. Apicella; A. Greco; A. Brunetti; B.K. Ambati; S.B. Helmers; I.E. Lundberg; O. Viklicky; J.H. Leusen; J.S. Verbeek; B.D. Gelfand; A. Bastos-Carvalho; S. De Falco; J. Ambati. Intravenous immune globulin suppresses angiogenesis in mice and humans. Signal transduction and targeted therapy 2016
S. Bogdanovich; Y. Kim; T. Mizutani; R. Yasuma; L. Tudisco; V. Cicatiello; A. Bastos-Carvalho; N. Kerur; Y. Hirano; J.Z. Baffi; V. Tarallo; S. Li; T. Yasuma; P. Arpitha; B.J. Fowler; C.B. Wright; I. Apicella; A. Greco; A. Brunetti; M. Ruvo; A. Sandomenico; M. Nozaki; R. Ijima; H. Kaneko; Y. Ogura; H. Terasaki; B.K. Ambati; J.H. Leusen; W.Y. Langdon; M.R. Clark; K.L. Armour; P. Bruhns; J.S. Verbeek; B.D. Gelfand; S. De Falco; J. Ambati. Human IgG1 antibodies suppress angiogenesis in a target-independent manner. Signal transduction and targeted therapy 2016
T. Mizutani; B.J. Fowler; Y. Kim; R. Yasuma; L.A. Krueger; B.D. Gelfand; J. Ambati. Nucleoside Reverse Transcriptase Inhibitors Suppress Laser-Induced Choroidal Neovascularization in Mice. Investigative ophthalmology & visual science 2015 Nov
B.D. Gelfand; C.B. Wright; Y. Kim; T. Yasuma; R. Yasuma; S. Li; B.J. Fowler; A. Bastos-Carvalho; N. Kerur; A. Uittenbogaard; Y.S. Han; D. Lou; M.E. Kleinman; W.H. McDonald; G. Núñez; P. Georgel; J.L. Dunaief; J. Ambati. Iron Toxicity in the Retina Requires Alu RNA and the NLRP3 Inflammasome. Cell reports 2015 Jun 23
B.J. Fowler; B.D. Gelfand; Y. Kim; N. Kerur; V. Tarallo; Y. Hirano; S. Amarnath; D.H. Fowler; M. Radwan; M.T. Young; K. Pittman; P. Kubes; H.K. Agarwal; K. Parang; D.R. Hinton; A. Bastos-Carvalho; S. Li; T. Yasuma; T. Mizutani; R. Yasuma; C. Wright; J. Ambati. Nucleoside reverse transcriptase inhibitors possess intrinsic anti-inflammatory activity. Science (New York, N.Y.) 2014 Nov 21
Y. Kim; V. Tarallo; N. Kerur; T. Yasuma; B.D. Gelfand; A. Bastos-Carvalho; Y. Hirano; R. Yasuma; T. Mizutani; B.J. Fowler; S. Li; H. Kaneko; S. Bogdanovich; B.K. Ambati; D.R. Hinton; W.W. Hauswirth; R. Hakem; C. Wright; J. Ambati. DICER1/Alu RNA dysmetabolism induces Caspase-8-mediated cell death in age-related macular degeneration. Proceedings of the National Academy of Sciences of the United States of America 2014 Nov 11
Y. Hirano; T. Yasuma; T. Mizutani; B.J. Fowler; V. Tarallo; R. Yasuma; Y. Kim; A. Bastos-Carvalho; N. Kerur; B.D. Gelfand; S. Bogdanovich; S. He; X. Zhang; M. Nozaki; R. Ijima; H. Kaneko; Y. Ogura; H. Terasaki; H. Nagai; I. Haro; G. Núñez; B.K. Ambati; D.R. Hinton; J. Ambati. IL-18 is not therapeutic for neovascular age-related macular degeneration. Nature medicine 2014 Dec
N. Kerur; Y. Hirano; V. Tarallo; B.J. Fowler; A. Bastos-Carvalho; T. Yasuma; R. Yasuma; Y. Kim; D.R. Hinton; C.J. Kirschning; B.D. Gelfand; J. Ambati. TLR-independent and P2X7-dependent signaling mediate Alu RNA-induced NLRP3 inflammasome activation in geographic atrophy. Investigative ophthalmology & visual science 2013 Nov 11
J. Ambati; J.P. Atkinson; B.D. Gelfand. Immunology of age-related macular degeneration. Nature reviews. Immunology 2013 Jun
V. Tarallo; Y. Hirano; B.D. Gelfand; S. Dridi; N. Kerur; Y. Kim; W.G. Cho; H. Kaneko; B.J. Fowler; S. Bogdanovich; R.J. Albuquerque; W.W. Hauswirth; V.A. Chiodo; J.F. Kugel; J.A. Goodrich; S.L. Ponicsan; G. Chaudhuri; M.P. Murphy; J.L. Dunaief; B.K. Ambati; Y. Ogura; J.W. Yoo; D.K. Lee; P. Provost; D.R. Hinton; G. Núñez; J.Z. Baffi; M.E. Kleinman; J. Ambati. DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88. Cell 2012 May 11
M.E. Kleinman; H. Kaneko; W.G. Cho; S. Dridi; B.J. Fowler; A.D. Blandford; R.J. Albuquerque; Y. Hirano; H. Terasaki; M. Kondo; T. Fujita; B.K. Ambati; V. Tarallo; B.D. Gelfand; S. Bogdanovich; J.Z. Baffi; J. Ambati. Short-interfering RNAs induce retinal degeneration via TLR3 and IRF3. Molecular therapy : the journal of the American Society of Gene Therapy 2012 Jan
S. Dridi; Y. Hirano; V. Tarallo; Y. Kim; B.J. Fowler; B.K. Ambati; S. Bogdanovich; V.A. Chiodo; W.W. Hauswirth; J.F. Kugel; J.A. Goodrich; S.L. Ponicsan; D.R. Hinton; M.E. Kleinman; J.Z. Baffi; B.D. Gelfand; J. Ambati. ERK1/2 activation is a therapeutic target in age-related macular degeneration. Proceedings of the National Academy of Sciences of the United States of America 2012 Aug 21
H. Kaneko; S. Dridi; V. Tarallo; B.D. Gelfand; B.J. Fowler; W.G. Cho; M.E. Kleinman; S.L. Ponicsan; W.W. Hauswirth; V.A. Chiodo; K. Karikó; J.W. Yoo; D.K. Lee; M. Hadziahmetovic; Y. Song; S. Misra; G. Chaudhuri; F.W. Buaas; R.E. Braun; D.R. Hinton; Q. Zhang; H.E. Grossniklaus; J.M. Provis; M.C. Madigan; A.H. Milam; N.L. Justice; R.J. Albuquerque; A.D. Blandford; S. Bogdanovich; Y. Hirano; J. Witta; E. Fuchs; D.R. Littman; B.K. Ambati; C.M. Rudin; M.M. Chong; P. Provost; J.F. Kugel; J.A. Goodrich; J.L. Dunaief; J.Z. Baffi; J. Ambati. DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration. Nature 2011 Mar 17
P.A. Pearson; T.L. Comstock; M. Ip; D. Callanan; L.S. Morse; P. Ashton; B. Levy; E.S. Mann; D. Eliott. Fluocinolone acetonide intravitreal implant for diabetic macular edema: a 3-year multicenter, randomized, controlled clinical trial. Ophthalmology 2011 Aug
P.J. Timoney; J.C. Pate; P.A. Pearson; J. Crandall. Bilateral central retinal artery occlusion in a patient with acute pancreatitis. Retinal cases & brief reports 2009 Summer
W.B. Lee; P.A. Pearson; K. Moreman. Central retinal artery occlusion and disc edema in a child. Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus 2002 Aug
W.B. Lee; H.S. O'Halloran; P.A. Pearson; H.A. Sen; S.H. Reddy. Airbags and bilateral eye injury: five case reports and a review of the literature. The Journal of emergency medicine 2001 Feb
H.S. O'Halloran; W.B. Lee; R.S. Baker; P.A. Pearson. Ophthalmoplegic migraine with unusual features. Headache 1999 Oct
P.A. Pearson; A.R. Piracha; H.A. Sen; G.J. Jaffe. Atovaquone for the treatment of toxoplasma retinochoroiditis in immunocompetent patients. Ophthalmology 1999 Jan
H.S. O'Halloran; J.R. Berger; R.S. Baker; W.B. Lee; P.A. Pearson; S. Ryan. Optic nerve edema as a consequence of respiratory disease. Neurology 1999 Dec 10
H.S. O'Halloran; P.A. Pearson; W.B. Lee; J.O. Susac; J.R. Berger. Microangiopathy of the brain, retina, and cochlea (Susac syndrome). A report of five cases and a review of the literature. Ophthalmology 1998 Jun
H.S. O'Halloran; K. Draud; M. Minix; A.K. Rivard; P.A. Pearson. Leber's neuroretinitis in a patient with serologic evidence of Bartonella elizabethae. Retina (Philadelphia, Pa.) 1998
D.P. Hainsworth; P.A. Pearson; J.D. Conklin; P. Ashton. Sustained release intravitreal dexamethasone. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 1996 Spring